The study, published in Nature Medicine, also concludes that those individuals homozygous for APOE4 also develop the disease earlier than those with other variants of the APOE gene. These findings ...

Notably, microglia spatially associated with amyloid plaques exhibited increased expression of TREM2 and ApoE compared to such cells in non-immunized controls, regardless of whether the treatment was ...

A LANDMARK genome-wide association study of 1,483 Lewy body disease (LBD) cases has identified APOE ε4 as the strongest ...

A MULTINATIONAL cohort study of 4,592 individuals has revealed significant sex and ancestry-based differences in how the APOE-ε4 gene influences Alzheimer’s disease biomarkers, with women of African ...