Researchers reveal that the loss of mucin-type O-glycosylation in the brain endothelial glycocalyx weakens the blood-brain ...

In a study with aging mice, Shi discovered significant changes in the sugary coating (glycocalyx) on cells that form the ...

to impair the BBB function in late phase of systemic inflammation. Microglia phagocytose astrocyte end feet which is one of the components of BBB. Disclaimer: AAAS and EurekAlert! are not ...

Changes in blood–brain barrier (BBB) properties and endocannabinoid system function contribute to stress responses and have been implicated in the development of mood disorders. Here ...

“Improving neurovascular integrity and BBB function in AD are important targets and may offer additive or synergistic treatment benefits in patients with AD. Furthermore, improving vascular ...

Designing BBB organoids posed a technical challenge ... indicating that the structures mimic the organ’s barrier function. To identify the cell populations in the assembloids, the researchers turned ...