Changes in brain development are accompanied by changes in the virus’s proclivity for different cell types. One nonclinical study showed that although the virus crossed the BBB, it preferentially ...

A membrane-like surface that prevents viruses and pathogens from entering the brain, the BBB is a hindrance to the direct entry of drugs into the brain similarly by filtering out active ...

A human polyomavirus, known as John Cunningham virus (JCV), has evolved the natural ability to penetrate and cross the BBB and enter the brain, where it causes progressive multifocal ...

Inflammation: The COVID-19 virus can cause inflammation that disrupts the blood-brain barrier (BBB). The BBB generally protects the brain from infections and medication side effects. A compromised ...