The blood–brain barrier acts as a strict control point for what can enter the brain, and is created by tight junctions between endothelial cells lining blood vessels, astroyctic endfeet and a ...

The blood-brain barrier is a set of characteristics of the brain's blood vessels that strongly limit exchanges between blood and brain tissue. This protects the brain from toxic components ...

Another SCFA, butyrate, and the microbes that produce it are also important for forming the barrier between the brain and the blood, which is called the blood-brain barrier. Gut microbes also ...

The blood-CSF barrier has been far less studied than the blood-brain barrier. Scientists have detected age-related changes in gene expression in the choroid plexus, and have linked these to increased ...

Researchers led by CHLA’s Jonathan D. Santoro, MD, have identified signs of neuroinflammation and dysfunction of the ...

In a study in aging mice, Shi has uncovered striking age-related changes in the sugary coating—called the glycocalyx—on cells that form the blood-brain barrier, a structure that protects the ...

The blood–brain barrier (BBB) is meant to protect the brain from noxious agents; however, it also significantly hinders the delivery of therapeutics to the brain. Several strategies have been ...

The research team recreated the blood-brain barrier membrane on the chip using ... Other devices use physical barriers, made from polymeric components. We think a biological one is superior." ...

They were watching brain scans of a woman named Bonny Hall, who lay inside an MRI machine just a few feet away. Earlier that day, Hall, who had been battling a brain tumor for eight years, had ...

One of those, the blood brain barrier (BBB), controls how molecules ... that the number of mucins compared to other glycocalyx components decreases with age. As the mucins disappear, the whole ...