The blood–brain barrier acts as a strict control point for what can enter the brain, and is created by tight junctions between endothelial cells lining blood vessels, astroyctic endfeet and a ...

A new study led by Jonathan D. Santoro, MD, Director of the Neuroimmunology Program at Children's Hospital Los Angeles, shows ...

Researchers of a new study have discovered that DSRD patients showed signs of neuroinflammation and blood-brain barrier ...

These cells lining the inside of your brain's blood vessels are tightly packed together, forming your blood-brain barrier.

The blood–brain barrier (BBB) is meant to protect the brain from noxious agents; however, it also significantly hinders the delivery of therapeutics to the brain. Several strategies have been ...

Getting mRNA into the brain could allow scientists to instruct brain cells to produce therapeutic proteins that can help ...

The blood-brain barrier serves as a protective shield, preventing many substances-including potentially beneficial therapies-from reaching the brain. While previous research from Mount Sinai ...

The Immense Importance of Brain-Derived Neurotrophic Factor Crossing the Blood-Brain Barrier According to research undertaken by Iughetti et al. (2011), the central nervous system and the ...

As we age, things don’t quite work the way they used to. Now Stanford researchers have identified how the breakdown of a sugary layer in the blood vessels that feed the brain could result in ...

The findings, in mouse models and isolated human brain tissue, were published in Nature Materials ("Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to the central nervous system").

Disruption of the blood-brain barrier is an early feature of lesion formation that correlates with clinical exacerbation and facilitates the entry of inflammatory medium and inflammatory cells.