BBB is already working with ethicists and regulatory experts to ensure its technology is developed responsibly.

A 3D model accurately mimicking the blood-brain barrier (BBB ... between cerebral blood vessels and neural cells, where the BBB plays a pivotal regulatory role. However, existing BBB models ...

On the flip side, the BBB blocks many promising therapeutics. However, system upgrades to the leading gene delivery ... much less than one viral genome per cell to the brain,” said Ben Deverman, a ...

Several carrier or transport systems, enzymes and receptors that control the penetration of molecules in the BBB endothelium have been identified. [1] Brain microvascular endothelial cells ...

In addition to a thick skull, the blood-brain barrier (BBB), a natural ... directly through cell membranes, whereas larger or water-soluble molecules face significant challenges. Most chemical drugs ...

The blood–brain barrier acts as a strict control point for what can enter the brain, and is created by tight junctions between endothelial cells ... (BBB) properties and endocannabinoid system ...

The lab-made hunk of brain is hooked up to 59 electrodes that create a stable neural network. This is all plugged into a “life-support unit” and hooked up to a proprietary software system.

A well-known in vitro model of the blood-brain barrier that is widely used in studies of neurodegenerative diseases and in preclinical research is made from the wrong kind of cells, according to ...