The Ability of Drugs to Penetrate the Blood–Brain Barrier The blood–brain barrier (BBB) is the main obstacle to the penetration of most drugs into the brain parenchyma and, in other types of ...
However, tPA can only be safely administered within 3 hours following stroke onset, as beyond this, the integrity of the blood–brain barrier (BBB) is compromised, and haemorrhagic complications ...
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Innovative 3D blood-brain barrier model enhances understanding of neuroinflammationA 3D model accurately mimicking the Blood-Brain Barrier (BBB) in a laboratory environment has been successfully developed by research teams led by Professor Jinah Jang from the Departments of ...
However, the effect of IL-1RA on blood-brain barrier disruption following ischemia-reperfusion has not been reported. METHODS: In this study, we investigated the effects of IL-1RA and a novel ...
Ischemic stroke results from an obstruction of a blood vessel supplying blood to the brain. The brain is an organ extremely sensitive to reduction of oxygen and energy, and brain damage is already ...
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