Santoro, MD, Director of the Neuroimmunology Program at Children's Hospital Los Angeles, shows evidence of dysfunction of the blood-brain barrier and inflammation in the central nervous system in ...

The blood–brain barrier acts as a strict control point for what can enter the brain, and is created by tight junctions between endothelial cells lining blood vessels, astroyctic endfeet and a ...

The aim is to overcome the blood-brain barrier which normally only allows certain nutrients and oxygen to pass through. Microbubbles that react to ultrasound are a particularly promising method for ...

were published in Nature Materials in a paper titled "Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to ...

Chiesi is interested in Aliada's modular delivery (MODEL) platform, which harnesses endogenous brain endothelial cell transport mechanisms – including transferrin and CD98 receptors – to usher ...

A new study led by Jonathan D. Santoro, MD, Director of the Neuroimmunology Program at Children's Hospital Los Angeles, shows ...