To maintain ploidy, unidirectional progression through the phases of the cell cycle (G1 → S → G2 → M → G1) is essential. To keep cells from regressing, the transitions of the mitotic cell ...
Some cell-cycle regulatory proteins must ... Cdt1 accumulates specifically during the G1 phase but is degraded during the G1/S transition after ubiquitination. Geminin accumulates during S ...
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