This massive endocytosis ("MEND") can be elicited in a variety of cell types with a range of different experimental manipulations, including internal calcium transients in the presence of ATP ...

The mechanisms whereby the ligands become competent to signal are not yet known, but probably entail endocytosis ... that resolves equivalent (purple) cells into distinct fates (blue and pink ...

In order to do this, cells have to use certain methods of transport, and one of them is endocytosis. The larger the molecule, the more difficult it is not only to absorb but also to transport it ...

In our lab, we focus on clathrin-mediated endocytosis, the predominant route for membrane internalisation in most cells. In addition to its role in endocytosis, the clathrin machinery also forms ...

In clathrin-mediated endocytosis, the cell membrane invaginates to take up metabolites, hormones, and proteins from the cell surface into intracellular vesicles. Cells employ several pathways for ...

A few years ago, the IISc team began investigating endocytosis, a cellular process often co-opted by viruses and bacteria to enter our cells. During their investigations, the researchers stumbled ...