How to clear the toxic tau protein that can lead to Alzheimer's and related diseases
The neurotransmitter glutamate is essential for regulating everything from mood to memory, but it can also encourage a toxic ...
Technology Networks10d
Targeting Lysosomes Could Halt Tau Accumulation in Alzheimer’s
A study reveals how glutamate drives tau accumulation in Alzheimer’s and related disorders. Researchers found that blocking ...
The Scientist2y
Scientists Uncover Major Pathway Cells Use to Mend Leaky Lysosomes
Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say. Holly Barker is a freelance journalist ...
pharmaphorum4d
MSD reaches $610m deal to buy lysosome biotech Caraway
It has a range of preclinical-stage projects that aim to harness lysosomes’ ability to clear ... lateral sclerosis (ALS), also known as motor neuron disease (MND). In 2020, the biotech was ...