The neurotransmitter glutamate is essential for regulating everything from mood to memory, but it can also encourage a toxic ...

A study reveals how glutamate drives tau accumulation in Alzheimer’s and related disorders. Researchers found that blocking ...

Damaged lysosomes are repaired by a lipid-based signaling pathway dubbed PITT that could be targeted to treat neurodegenerative disease, its discoverers say. Holly Barker is a freelance journalist ...

Feng Wei at the Institute of Biophysics, Chinese Academy of Sciences, has made significant strides in understanding the BORC complex, a key player in lysosome transport and localization.

It has a range of preclinical-stage projects that aim to harness lysosomes’ ability to clear ... lateral sclerosis (ALS), also known as motor neuron disease (MND). In 2020, the biotech was ...