Shihabeddin et al utilized single-cell RNA-Seq analysis of adult P23H zebrafish animals to identify transcription factors (e2fs, Prdm1a, Sp1) expressed selectively in neural progenitors and immature ...

Retinal measures included neuronal parameters (retinal nerve fiber layer and ganglion cell-inner plexiform layer) assessed using optical coherence tomography and microvascular parameters ...

In the absence of Strip1, retinal ganglion cells die, and other neurons take their place, resulting in defects in the inner plexiform layer.