Learn how nanoparticles cross the blood-brain barrier (BBB) and explore their potential in treating neurological disorders ...
The blood–brain barrier acts as a strict control point for what can enter the brain, and is created by tight junctions between endothelial cells lining blood vessels, astroyctic endfeet and a ...
The blood–brain barrier (BBB) is meant to protect the brain from noxious agents; however, it also significantly hinders the delivery of therapeutics to the brain. Several strategies have been ...
were published in Nature Materials in a paper titled "Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to ...
In an early-stage clinical trial, the therapy nearly doubled the expected survival time of young patients. Still, experts ...
ABL Bio’s first-in-class bispecific antibodies for Parkinson’s disease combine unprecedented blood–brain barrier penetration with a robust mechanism of action for improved therapeutic efficacy.
Medical Xpress on MSN12d
Breakthrough study led by CHLA neurologists links blood-brain barrier dysfunction and inflammation with Down syndrome regression disorderResearchers led by CHLA’s Jonathan D. Santoro, MD, have identified signs of neuroinflammation and dysfunction of the ...
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