A new research study led by Jonathan D. Santoro, MD, Director of the Neuroimmunology Program at Children’s Hospital Los ...

Researchers of a new study have discovered that DSRD patients showed signs of neuroinflammation and blood-brain barrier ...

A new analysis provides substantial evidence that paramagnetic rim lesions drive disability in MS and are targetable with a blood-brain barrier-penetrating therapy.

For years, scientists studying brain aging have focused on proteins and DNA. But what if a crucial piece of the puzzlehas ...

Myrobalan's experimental therapy MRO-002 is a GPR17 antagonist that's made to promote myelin repair in people with MS and ...

These cells lining the inside of your brain's blood vessels are tightly packed together, forming your blood-brain barrier.

A generation ago, a diagnosis of multiple sclerosis often meant a steady ... there’s a breakdown of the blood-brain barrier, a selectively permeable envelope of blood vessels and tissue that ...

More information: Omar M. F. Omar et al, Endothelial TDP-43 depletion disrupts core blood–brain barrier pathways in neurodegeneration, Nature Neuroscience (2025). DOI: 10.1038/s41593-025-01914-5 ...

In a study in aging mice, Shi has uncovered striking age-related changes in the sugary coating – called the glycocalyx – on cells that form the blood-brain ... into the brain, offering hope for ...

In a study in aging mice, Shi has uncovered striking age-related changes in the sugary coating—called the glycocalyx—on cells that form the blood ... from multiple sclerosis to brain cancer.