This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when ...

Hospital studies suggest that scrub typhus is a leading cause of severe undifferentiated fever in regions across Asia where the disease is endemic, but the population-based incidence of infection ...

Dr. David M. Dudzinski: A 72-year-old woman was evaluated at this hospital because of altered mental status. Five years before the current admission, the patient underwent transurethral resection ...

Patients with aneurysmal subarachnoid hemorrhage often have anemia, but evidence guiding transfusion in these patients is limited. New research findings evaluating a liberal versus restrictive ...

In patients with bloodstream infection, early, appropriate antibiotic therapy is important, but the duration of treatment is uncertain. New research findings on treatment duration in hospitalized ...

Whether surgical axillary staging can be omitted without compromising survival in women with early-stage breast cancer undergoing breast-conserving therapy has been unclear. New research findings ...

A woman was seen for evaluation of gastric polyposis, a condition her uncle also had. On upper endoscopy, innumerable polyps in the gastric corpus and an area of pale mucosa along the greater ...

A 46-year-old patient presented to a clinician to request initiation of estrogen therapy. . . . Each interactive case presents an evolving patient history and a series of questions and exercises ...

A 2-year-old boy presented with a 1-week history of itchy, red spots. Tense vesicles, erosions, and inflammatory plaques were seen. Direct immunofluorescence revealed a linear band of IgA at the ...

THE beginning clinical clerk, the house officer and the practicing physician are all confronted with conditions that are frustrating in every phase of medical action. The purpose of this article ...

The patients studied on the medical wards of the Boston City Hospital had been admitted primarily for treatment of severe liver disease or the complications of alcoholism. One patient was admitted ...

Alex Keuroghlian is an associate professor of psychiatry at Harvard Medical School and the director of the Division of Public and Community Psychiatry at Massachusetts General Hospital. Stephen ...