Typically, endocytosis is facilitated with a protein called clathrin, but clathrin was not involved in the absorption of small extracellular vesicles into their target cells.

Classically, endocytosis involves the formation of clathrin-coated carriers that bud from the plasma membrane by dynamin-dependent mechanisms. Recently, several clathrin-independent endocytic ...

FIGURE 1. Major Forms of Endocytosis. In addition to the well-studied clathrin-mediated endocytic pathway, a variety of clathrin-independent pathways exist in eukaryotes. Shown here, many of the known ...

Xuefei Tian Patricia Bunda Shuta Ishibe * Department of Internal Medicine, Yale School of Medicine, New Haven, CT, United States Endocytosis is a mechanism that internalizes and recycles plasma ...

Thank you for submitting your article "The AP-2 complex has a specialized clathrin-independent role in apical endocytosis and polar growth in fungi" for consideration by eLife. Your article has been ...

Transporter internalization, similar to apical endocytosis, requires actin polymerization and functional endocytic factors SagA End3 or SlaB End4. Curiously, the role of clathrin or AP-2 in apical or ...

Abstract Endocytosis controls many functions including nutrient uptake, cell division, migration and signal transduction. A clathrin‐ and caveolin‐independent endocytosis pathway is used by important ...

Using similar cells, we have examined if this is also the case for clathrin-independent pathways, including caveolae-mediated endocytosis and macropinocytosis. We observed impaired caveolin-1 ...

In this study, we investigated the action and targets of Rac1, which our laboratory has previously suggested to be involved, similarly to RhoA, in the endocytosis of IL‐2Rβ (Lamaze et al, 2001). Thus, ...

CD40 Endocytosis via Clathrin-Independent but Caveolae-Dependent Pathway We and others 19,22 have demonstrated that G28.5 mimicks recombinant sCD40L to efficiently and specifically induce ...