Cyclin A2 and Cyclin B1 serve as S phase and G2-M markers, respectively. pH3 at Ser10 serves as a mitotic marker. GAPDH serves a loading control. C) Heatmap illustrating differential abundance of ...

Cyclin A2 and Cyclin B1 serve as S phase and G2-M markers, respectively. pH3 at Ser10 serves as a mitotic marker. GAPDH serves a loading control. C) Heatmap illustrating differential abundance of ...

Enter the Minisforum MS-A2, a mini PC that challenges the notion that compact systems must compromise on performance. With a 16-core AMD Ryzen 9 9955HX processor, support for up to 96GB of DDR5 ...

The MINISFORUM MS-A2 is a compact desktop computer with a 55-watt, 16-core, 32-thread AMD Ryzen 9 9955HX “Fire Range” processor, and plenty of expansion options including support for up to ...

The MINISFORUM MS-A2 is a small desktop computer that combines a high-end AMD Ryzen mobile processor with desktop-class performance with a design that offers plenty of expansion options.

One specific hit, called S656 acts as a molecular glue degrader (MGD), that mediates the CRL4-dependent proteolysis of cyclin K. Structurally, S656 features a moiety that binds to the ATP binding site ...

The poster will showcase the design and ongoing progress of its Phase 1 study of CID-078 (NCT06577987), a first-in-class, oral macrocycle cyclin A/B RxL inhibitor. The abstract will be featured in a ...

Cyclin E1 (CCNE1) expression has been associated with replicative stress and defects in double-strand break repair in multiple tumor types; however, this has yet to be demonstrated in ovarian cancer.

School of Biomedical Engineering & State Key Laboratory of Advanced Medical Materials and Devices, ShanghaiTech University, Shanghai 201210, China School of Pharmacy, East China University of Science ...

While the cyclin-dependent kinase inhibitor AT7519 induces neutrophil apoptosis to promote inflammation resolution in preclinical models of lung inflammation, its potential efficacy in ARDS has not ...