It was discovered that inhibition of notch receptor-1 (Notch-1) signaling, deletion of the immediate early response gene X-1 (IEX-1), and ... This suggests that whereas M2 macrophages block ...

Patients at risk for FECD should undergo genetic screening to help assess their risk of vision loss. Genetic screening for CTG18.1 expansions can identify patients at elevated risk of vision loss ...

Based on this study, it was found that berberine treatment could reduce podocyte injury by downregulating TGF-β1 receptor expression, which reduced apoptosis and increased podocyte adhesion ability ...