Interestingly, this study noted an increase in the proportion of M1 macrophages and a decrease in M2 macrophages in CRC, contradicting the M1/M2 polarization theory. Functional analyses suggests ...

In the prevention of recurrence and metastasis in early-stage lung adenocarcinoma, identification of molecular markers is key ... as were high-density M1 type macrophages (HR, 2.67; P ...

Tumor-promoting TAMs comprise subpopulations characterized by distinct markers and unique transcriptional ... suggests that the polarization state of macrophages is far more complex than the ...

smu.edu.cn Objectives To investigate the roles and regulatory mechanisms of synovial macrophages and their polarisation in the development of osteoarthritis (OA). Methods Synovial tissues from normal ...

M1-type macrophages primarily function in the early inflammatory phase by secreting pro-inflammatory factors, while M2-type macrophages actively contribute ... and myofibroblast (a-SMA) markers.

Bone marrow derived macrophages were prepared and polarised to classic (M1) or alternative (M2) activation states. Markers for macrophage phenotype were measured using quantitative RT-PCR. Results ...

FK866-induced NAD depletion skews monocyte/macrophage biology away from a proinflammatory M1 towards an anti-inflammatory M2 phenotype. FK886 diminishes cytokine release from human IBD-derived lamina ...

The MacBook Air M4 introduces a flat, streamlined design, moving away from the iconic wedge-shaped profile of the M1. This updated aesthetic aligns with the design language introduced with the M2 ...