Background: Pyrin is a newly recognised intracellular regulator of inflammation, and mutations in MEFV, the gene encoding pyrin, are the cause of familial Mediterranean fever. Objective: To determine ...

FMF affects as many as 1 in 200 people in these populations. FMF is caused by mutation in the MEFV gene, which encodes a protein called pyrin found in white blood cells. The mutated protein disrupts ...

Mutations in the ELANE gene have been associated with cyclic neutropenia and ... Allogeneic transplant in Elane and mefv mutation positive severe cyclic neutropenia: Review of prognostic factors for ...

The one-off treatment highlights the promise of a new type of gene editing and the challenges of using it to treat extremely rare genetic diseases. Doctors say they constructed a bespoke gene ...

A baby born with a rare and dangerous genetic disease is growing and thriving after getting an experimental gene editing treatment made just for him. Researchers described the case in a new study ...

A baby born with a rare and dangerous genetic disease is growing and thriving after getting an experimental gene editing treatment made just for him. The baby, KJ Muldoon of Clifton Heights ...

Featured Host, "CBS Mornings;" Anchor, "CBS News 24/7" Vladimir Duthiers is a featured host of "CBS Mornings" and serves as anchor for CBS News 24/7. The Peabody Award- and Emmy Award-winning ...

You can reach Jason on Signal at JasonMast.05. NEW ORLEANS — The mood at the annual meeting of the American Society of Cell and Gene Therapy isn’t amazing. The biotech market has been bad for ...

A flexible, intrinsically disordered region (IDR) in the TAF2 protein directs its movement between gene promoters and nuclear speckles, linking transcription initiation and RNA processing.

Gene and Betsy were laid to rest and remembered in a small, private memorial held recently in Santa Fe Gene Hackman died of hypertensive and atherosclerotic cardiovascular disease, while his wife ...

A physician reflects on the burden of caregivers and the tragic story of Gene Hackman and Betsy Arakawa. He also emphasizes the importance of community support for caregivers and encourages acts ...