In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks (DSBs) formation. Meiosis, a specialized form of cell division in most ...

How is the same process responsible for genetic recombination and diversity also the cause of aneuploidy? Understanding the steps of meiosis is essential to learning how errors occur.

(A) In mitosis, diploid cells replicate chromosomes during S phase and segregate sister chromatids during M phase, so that diploid daughter cells are produced. (B) In meiosis, two chromosome ...

Researchers at the Stowers Institute discovered how selfish genes manipulate inheritance by forming toxic protein clusters. These genes, found in yeast, evolve rapidly to outpace genetic suppression ...

At the LMB, her group carried out the first studies of meiosis in live human oocytes and developed strategies for high content screens for meiotic genes in mammals. Director and Scientific Member at ...