In this study, the impact of C-Nap1 on spermatogenesis using C-Nap1 knockout mouse models was investigated. Single-cell RNA ...

When cells split to create eggs and sperm, they must undergo a crucial process called "meiotic crossover recombination." This mechanism ensures that genetic material is properly shuffled between ...

Women have a higher proportion of key immune cells between puberty and menopause, which may be linked to the sex hormone oestrogen and explain why they are less susceptible to certain infectious ...

On this page we present research groups and units in the area of biophysics at Karolinska Institutet. The list is compiled automatically from our research information database and is based on the ...

Lipoproteins transport cholesterol and triglycerides to cells in the body. An excess of lipoproteins can result in the storage of these lipids in inappropriate tissues. This provokes the immune system ...

In combination with previous work, we establish Mer2 as a keystone of the DSB machinery by bridging key protein complexes involved in the initiation of meiotic recombination. Using a combination of ...

Meiotic chromosomes are highly compacted yet remain transcriptionally active. To understand how chromosome folding accommodates transcription, we investigated the assembly of the axial element, the ...