Harvey Silikovitz just wowed Jeopardy! audiences with his stunning win on Monday’s (March 10) game show. He beat eight-day champion Laura Faddah by answering 35 questions correctly and only one ...

Validation of mature cortical neuron properties and effect of psilocin on cell surface-located 5-HT2A receptor presentation. Credit: eLife (2025). DOI: 10.7554/eLife.104006.1 ...

When exposed to glutamate, these organoids—especially those from diseased patients—showed toxic tau buildup and nerve cell death ... blocking KCTD20 activated lysosomes, the brain’s ...

Researchers at The Ohio State University led by Dr. Benjamin Segal, professor and chair of the department of neurology at The Ohio State University Wexner Medical Center and College of Medicine, have ...

Further experiments showed that blocking this gene’s activity activated lysosomes—cellular compartments responsible ... KCTD20 suppression mitigates excitotoxicity in tauopathy patient organoids.

In a USC Stem Cell-led study published in Neuron, scientists describe a new ... this gene activated cellular compartments called lysosomes, which enveloped the toxic tau proteins and expelled ...

What Is Ulnar Tunnel Syndrome? Ulnar tunnel syndrome is pain, tingling, or numbness in your hand, caused by a pinched nerve in your wrist. It isn’t pleasant, but treatments and simple changes to ...

β-GC hydrolyzes glucosylceramide (GluCer) into glucose and ceramide in the lysosome, and the loss of its activity leads to GluCer accumulation in different tissues. In severe cases, enzymatic ...

Ulnar nerve entrapment happens when there’s pressure on the ulnar nerve. The ulnar nerve travels from the shoulder to the pinky finger. It can cause symptoms like muscle weakness and numbness ...