Here, we explored how NMDARs signal in tLTD. We found that, regardless of frequency, L5 PC→PC tLTD relies on the non-ionotropic preNMDAR signaling pathway mediated by JNK2, which helps to resolve the ...

Nintendo Switch 2 pre-orders have been delayed in the U.S. as confirmed to Tom's Guide via an official statement. Switch 2 was set to be available to pre-order this week (on April 8) but due to a ...

Long-term depression (LTD) encompasses a family of synaptic plasticity mechanisms that can be triggered by the synaptic or pharmacological activation of glutamate receptors — in particular ...

Investors may trade in the Pre-Market (4:00-9:30 a.m. ET) and the After Hours Market (4:00-8:00 p.m. ET). Participation from Market Makers and ECNs is strictly voluntary and as a result, these ...

Investors may trade in the Pre-Market (4:00-9:30 a.m. ET) and the After Hours Market (4:00-8:00 p.m. ET). Participation from Market Makers and ECNs is strictly voluntary and as a result, these ...

Our English for Academic Purposes (EAP) presessional programme will ensure that you are well prepared for your studies. Develop the English language and academic skills you will need to study at LSE ...

Brain rhythms emerge from the mean-field activity of networks of neurons. There have been many efforts to build mathematical and computational embodiments in the form of discrete cell-group activities ...

Behavioral flexibility is critical to survival. Animals must adapt their behavioral responses based on changes in the environmental context, internal state, or experience. Studies in Drosophila ...

aNational Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, MD, USA bNational Institute on Drug Abuse, National Institutes of Health, Rockville, MD, USA Drug ...

Apr. 7, 2025 — Scientists find the protein IL-17 that fights infection also acts on the brain, inducing anxiety or sociability. This adds to evidence that immune ...