The data convincingly show that the transcription factor Sp1 regulates ephrin-mediated axon guidance in the spinal cord. Although the authors show that Sp1 and its co-activators p300 and CBP are ...

Sodium-glucose transport protein 2 (SGLT2) inhibitors are a class of medications used to treat type 2 diabetes. They’re also known as gliflozins. SGLT2 inhibitors prevent the reabsorption of ...

Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana−Champaign, Champaign, Illinois 61801, United States Department of Chemistry, University of Illinois at ...

We may earn an affiliate commission from links. Protein seems to be on everyone’s mind right now, not because of new findings or weird social media debates but because the more we take our ...

Cell membrane proteins hide secret gateways that can be ... because a significant portion of existing drugs target them to act on cells. In fact, 34% of FDA-approved drugs are based on these ...

Previously unknown access points in cell membrane proteins have been discovered ... significant portion of existing drugs target them to act on cells. In fact, 34% of FDA-approved drugs are ...

Small Molecule Therapeutic Discovery, Amgen Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States ...

Kinases regulate nearly every aspect of cellular function – they act ... inhibitors disrupt both cell cycle control and transcription, making them effective for aggressive cancers. CDK9 inhibitors ...

On March 15, US President Donald Trump mass deported Venezuelan migrants and transported them using two aircrafts to a prison in El Salvador using a controversial wartime legislation - the 1798 Alien ...

Kaken Pharmaceutical will hand Alumis $40 million in the near term for the rights to develop a late-stage tyrosine kinase 2 (TYK2) inhibitor as a dermatology treatment in Japan. The drug in ...