Abstract Rare and common genetic variants contribute to the risk of atrial fibrillation (AF). Although ion channels were among the first AF candidate genes identified, rare loss-of-function variants ...

Upon review of this body and the described ECG findings, certain common patterns ... cocaine use and AV conduction as assessed by PR interval length appears to be somewhat contradictory.

Topical cocaine caused a significant increase in heart rate from 96.7 ± 21.9 to a peak of 120.1 ± 15.6 bpm (p < 0.001 ... drug exposure to first noted electrocardiogram abnormality or ...