Amyloid precursor protein (APP)-derived amyloid-β (Aβ) peptides form pathological aggregates in Alzheimer’s disease (AD).

Researchers from The University of Osaka find the key proteins that maintain optimal pH within the Golgi apparatus by ...

Human egg cells wait in the ovaries from before birth until they are finally called upon, sometimes 40 years later, to kick ...

In this valuable study, the authors provide a simple yet elegant approach to identifying therapeutic targets that synergize to prevent therapeutic resistance in ovarian cancer using cell lines, ...

A recent study published in Genes & Diseases reveals a novel role of XPR1 in promoting ovarian cancer growth by regulating autophagy and MHC-I expression. The research, conducted by scientists from ...

Contrary to long-standing assumptions, human egg cells stay pristine for decades not by ramping up waste disposal, but by ...

Identifying new ways to disrupt the progression of diseases like Alzheimer's or cancer is a primary outcome of biological research. Understanding the ...

Researchers at the University of Tsukuba have discovered a unique biphasic cellular response triggered by tetrandrine, a ...

Abstract Summary Pharmacological enhancement of endoplasmic reticulum (ER) proteostasis is an attractive strategy to mitigate pathology linked to etiologically-diverse protein misfolding diseases.

Discover what glycan analysis can reveal about protein behavior and how it can be used to boost biologic performance and ...