Background High-level exposure to crystalline silica dust is the key factor in silicosis. Long-term exposure to low-level silica dust, for example, lower than that in occupational exposure limits, ...

Background Inhaled mannitol provokes bronchoconstriction via mediators released during osmotic degranulation of inflammatory cells, and, hence represents a useful diagnostic test for asthma and model ...

History of Medicine Department, Medical School, University of Athens, Athens, Greece Correspondence to Dr Marianna Karamanou, History of Medicine Department, Medical School, University of Athens, 4 ...

Correspondence to Michael A Mitchell, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; MichaelA.Mitchell{at}lhsc.on.ca Background Pleural ...

Intensive care unit acquired weakness (ICUAW) is now a well-known entity complicating critical illness. It increases mortality and in the critical illness survivor it is associated with physical ...

Department of Human Biology, Nutrition and Toxicology Research Institute (NUTRIM), Maastricht University, Maastricht, The Netherlands Dr A M W J Schols, NUTRIM School for Nutrition, Toxicology and ...

Oxford Centre for Respiratory Medicine, University of Oxford and Churchill Hospital, Oxford OX3 7LJ, UK Correspondence to: Professor J R Stradling Oxford Centre for Respiratory Medicine, University of ...

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, National Jewish Health, Denver, Colorado, USA Background: While acute lung injury (ALI) is among the most serious ...

Introduction Tyrosine kinase inhibition has shown inconsistent success in the treatment of idiopathic pulmonary fibrosis (IPF). While a study of imatinib showed no impact on survival or lung function ...

Background Patients with the connective tissue disorder Ehlers-Danlos syndrome (EDS) often suffer from fatigue, excessive daytime sleepiness and impaired quality of life. Obstructive sleep apnoea (OSA ...