Figure 2: Inhibition of caspase 3, apoptosis (caspase ... in viral-induced disease and suggest that apoptosis and apoptotic signalling pathways may provide novel targets for treatment of virus ...

Apoptosis is regulated by a family of ... be activated by both the receptor and mitochondria-mediated pathways. Mice deficient in caspase-3 (caspase-3 −/−) have defective neuronal apoptosis ...

Scientists commonly use caspase assays to evaluate apoptosis, evaluating caspase activation—a hallmark of apoptosis initiation—with fluorescent dyes. Researchers often perform multiplex caspase assays ...

The primary interest of our lab is to investigate the molecular mechanisms of apoptosis and how they impact human ... disk confocal microscope to perform single cell analysis of caspase pathways.

Caspase activity in MCF-7 and T47D cells ... CCNG1 levels but also activates the NF-κB signaling pathway, leading to increased apoptosis in MCF-7 cells. Overall, our study highlights TNIP1 ...

Disrupting the fast-paced but fragile pyrimidine synthesis pathways ... and instantly sets off a series of caspase enzymes that help initiate apoptosis (cell death). "Our study shows how cancer ...

In particular, the MAP kinase pathway was predicted to be ... was observed to significantly reduce caspase-3/7 activation, a hallmark of apoptosis, by nearly 50%, thus suggesting that the ...

A systematic review published in Discover Oncology explores the anticancer efficacy of medicinal plant extracts in treating Oral Squamous Cell Carcinoma (O | Plants And Animals ...