The universality of calcium as an intracellular messenger depends on its enormous versatility. Cells have a calcium signalling toolkit with many components that can be mixed and matched to create ...

Despite the challenge, seeking a better understanding of human nervous system function and the natural world beyond is key to ...

Lower motor neuron (LMN) syndromes are clinically characterised by muscle atrophy, weakness and hyporeflexia without sensory involvement. They may arise from disease processes affecting the anterior ...

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), led by Jorge Alegre-Cebollada, has developed an ...

Astrocytes, once thought to be the brain’s housekeepers, may actually be silent powerhouses of memory.

European Commission approves Roche’s Evrysdi tablet to treat spinal muscular atrophy: Basel Thursday, June 5, 2025, 09:00 Hrs [IST] Roche announced that the European Commission ...

The human body is a veritable cellular highway with up to 37 trillion cells traveling about and carrying out all essential ...

Epilepsy is primarily treated symptomatically - that is, the majority of the available medications aim to suppress seizures ...

Roche leads the clinical development of Evrysdi as part of a collaboration with the SMA Foundation and PTC Therapeutics.

Figure 1: Structure and motility models of KIF5 and KIF1A. The kinesin motor domain is composed of a single globular catalytic core and a short strand 'neck linker'. The catalytic core contains ...

cDepartment of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, the Netherlands dBiostatistics & Research Support, Julius Center for Health Sciences and Primary Care, University ...