By attaching hydrophobic groups like cholesterol, which anchor them into the lipid membrane’s hydrophobic core, scientists have been able to alter the membrane’s properties, such as increasing ...

Readers are referred to excellent recent reviews 5,6 for a discussion of membrane association by unstructured clusters of basic and hydrophobic ... that is ubiquitous in cell membranes (Table ...

Membrane proteins are proteins found in cell membranes ... glycophosphatidylinositol (GPI) or a hydrophobic protein patch. The complexity of living systems makes methods for chemically ...

Pharmaceutical Technology serves as the connection to bio manufacturing and development, featuring regulatory updates and ...

Endogenous intracellular allosteric modulators of GPCRs remain largely unexplored, with limited binding and phenotype data available. This gap arises from the lack of robust computational methods for ...

Nuclera has enhanced its eProtein Discovery™ system with a dedicated membrane protein production workflow, enabling researchers to express and purify functional membrane proteins in just 48 ...

Global research shows how plankton adapt their cell membranes to survive changing ocean light, nutrients, and temperature.

This important study presents a compelling theoretical framework for understanding phase separation of membrane-bound proteins, with a focus on the organization of tight junction components. By ...

Mitochondria Are More Than Powerhouses—They’re the Motherboard of the Cell ...

This balancing act allows for the formation of membrane domains -- self-assembling structures that are believed to organize proteins in cell membranes. The work tests and revises a 50-year old ...

A team of researchers studied the properties of membranes to understand how these cellular structures influenced the chemistry of life on Earth as it began. How life arose remains a looming ...

Scientists have discovered tumors can tap a nontraditional pathway to acquire lipoproteins—molecules that transport fat in ...