Esophageal squamous cell carcinoma (ESCC) is a deadly cancer with particularly high prevalence in East Asia. While ...

The authors study how apolipoprotein L1 variants impact inflammation and lipid accumulation in macrophages. The findings will be useful for researchers investigating macrophage metabolism and ...

A silk-based nanocomposite hydrogel delivers dexamethasone + kartogenin to reduce inflammation and regenerate cartilage ...

Adenosine deaminase 2 (ADA2) plays a critical role in immune regulation, particularly in monocyte differentiation and activation. Unlike ADA1, which primarily functions intracellularly, ADA2 can be ...

By investigating murine TAMs, we identify distinct polarization states (M0, M1, and M2) through marker free vibrational and autofluorescence signatures. Our findings highlight lipidome and metabolic ...

Lee, K.Y. (2019) M1 and M2 Polarization of Macrophages A Mini-Review. Medical Biological Science and Engineering, 2, 1-5.

Activated macrophages are key drivers of vascular inflammation in KD. The aim of this study was to examine differences in M1 and M2 macrophage marker expression in patients with KD. Blood samples were ...

M1 and M2 macrophage-type responses kill or repair in vivo. The unique ability of macrophages to make these polar opposite type of responses provides primary host protection and maintains tissue ...

Mice lacking GSK3α in myeloid cells had a less inflammatory and more anti-inflammatory plasma cytokine profile. Macrophages within atherosclerotic lesions of myeloid GSK3α-deficient mice, but not of ...