Other rules of synaptic plasticity appear to have a bigger effect and better explain how brain activity continually reshapes the way memories are recorded in the brain.

Researchers devised a process to convert a skin cell directly into a neuron, eliminating the need to generate induced pluripotent stem cells. Such neurons could be used to treat spinal cord ...

Inhibitory circuits in the basal amygdala (BA) have been shown to play a crucial role in associative fear learning. How the excitatory synaptic inputs received by BA GABAergic interneurons are ...

Corticofugal projections to evolutionarily ancient, subcortical structures are ubiquitous across mammalian sensory systems. These ‘descending’ pathways enable the neocortex to control ascending ...

Parkinson’s disease (PD) is a common and complicated neurodegenerative disease with motor deficits, including static tremor, rigidity, bradykinesia, and non-motor dysfunctions, such as hyposmia, sleep ...

The kinesin I family of motor proteins are crucial for axonal transport, but their roles in dendritic transport and postsynaptic function are not well-defined. Gene duplication and subsequent ...