How to clear the toxic tau protein that can lead to Alzheimer's and related diseases
In a USC Stem Cell-led study published in Neuron, scientists describe a new ... this gene activated cellular compartments ...
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Inability of cells to recycle fats can spell disease: Study reveals how a protein helps transport fats out of lysosomes
Fats and other cellular materials reach the lysosome through three main pathways: endocytosis, phagocytosis, and autophagy. In endocytosis, the cell takes in materials from outside by wrapping ...
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MSD reaches $610m deal to buy lysosome biotech Caraway
It has a range of preclinical-stage projects that aim to harness lysosomes’ ability to clear ... lateral sclerosis (ALS), also known as motor neuron disease (MND). In 2020, the biotech was ...
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Targeting Lysosomes Could Halt Tau Accumulation in Alzheimer’s
Further experiments showed that blocking this gene’s activity activated lysosomes—cellular compartments responsible ... KCTD20 suppression mitigates excitotoxicity in tauopathy patient organoids.