Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged ...

Any proteins that are destined for a lysosome are delivered to the lysosome interior when the vesicle that carries them fuses with the lysosomal membrane and joins its contents. In contrast ...

Because the STING protein has multiple functional regions spanning the cell membrane, the researchers did additional experiments to determine which region might be responsible for lysosome generation.

Using a version of the enzyme which localizes to lysosomes and a chemical known to puncture the lysosomal membrane, he was able to biotinylate all the proteins surrounding the damaged organelle. Tan ...

Genes associated with lysosomal dysfunction increase the risk of Parkinson’s disease (PD), according to a study led by ...

Researchers say the work is a significant step forward in modeling protein-membrane interactions—resulting in a more accurate and scalable tool for studying cellular membranes, which could have ...