Systemic therapy represents the standard of care treatment for patients with advanced hepatocellular carcinoma (HCC). Given ...

Background Fibrolamellar carcinoma (FLC), a rare and fatal liver cancer lacking effective drug therapy, is driven by the DNAJ ...

The earth’s climate is changing because of increasing concentrations of greenhouse gases in the atmosphere, which has already warmed by more than 1°C compared with preindustrial times. The aim of ...

1 School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong 2 Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong 3 Department of ...

Background Inflammatory bowel diseases (IBDs) are characterised by dysbiosis and a leaky gut. The NADPH oxidase dual oxidase 2 (DUOX2) is upregulated in patients with IBD, yet its role in driving the ...

Introduction Prompt treatment of IBD is essential to improve symptoms and prevent adverse outcomes. Having identified delays in treatment pathways in patients first diagnosed with IBD at endoscopy, a ...

Correspondence to Dr Eileen Morgan, International Agency for Research on Cancer, 69372 Lyon CEDEX 08, France; morgane{at}iarc.who.int Objective Colorectal cancer (CRC) is the third most common cancer ...

Correspondence to Brian B Scott, Department of Medicine, Lincoln County Hospital, Lincoln LN2 5QY, UK; drbbscott{at}aol.com Iron deficiency anaemia (IDA) occurs in 2–5% of adult men and postmenopausal ...

Lymphocytic gastritis is a histopathological entity characterised by the accumulation of small lymphocytes in the surface and foveolar epithelium. In order to investigate the correlation between ...

Background Acute appendicitis is a local intestinal inflammation with unclear origin. The aim was to test whether bacteria in appendicitis differ in composition to bacteria found in caecal biopsies ...

Correspondence to Professor Jin-Woo Bae, Department of Life and Nanopharmaceutical Sciences and Department of Biology, Kyung Hee University, Seoul 02447, Republic of Korea; baejw{at}khu.ac.kr; ...

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