Preclinical and observational studies suggest that exercise may improve cancer outcomes. However, definitive level 1 evidence ...

Yearly Covid-19 Booster Recommendations in Canada, Europe, and Australia. Although the rapid development of multiple Covid-19 vaccines in 2020 represents a major scientific, medical, and ...

Enteral nutrition is defined as the provision of essential nutrients through an enteral tube to prevent or treat disease-related malnutrition in patients who are unable to consume adequate ...

In the peripheral airways of patients with chronic obstructive pulmonary disease, as compared with normal peripheral airways, there is airflow limitation due to a variable mixture of loss of ...

This open-label, randomized, controlled trial involved couples in which a woman had bacterial vaginosis and was in a monogamous relationship with a male partner. In the partner-treatment group ...

Endovascular treatment (EVT) of stroke with large-vessel occlusion is known to be safe and effective. The effect of EVT for occlusion of medium or distal vessels is unclear. We randomly assigned ...

New catheter materials for peripherally inserted central catheters (PICCs) may reduce the risk of device failure due to infectious, thrombotic, and catheter occlusion events. However, data from ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when ...

Currently licensed and approved malaria subunit vaccines provide modest, short-lived protection against malaria. Immunization with live-attenuated Plasmodium falciparum malaria parasites is an ...

The mechanisms involved in the development of cardiovascular disease in persons with type 1 diabetes are shown. Data from randomized, controlled trials examining the effect of statins on ...

Neutrophils constitute the main infiltrating cell type in Behçet’s syndrome lesions. By producing excessive levels of reactive oxygen species and releasing neutrophil extracellular traps ...

Primary biliary cholangitis is a rare, chronic cholestatic liver disease characterized by the destruction of interlobular bile ducts, leading to cholestasis and liver fibrosis. Whether elafibranor ...