Aug 14, 2024 · Clindamycin is an antibiotic that fights bacteria in the body. Clindamycin is used to treat serious infections caused by bacteria. Clindamycin is usually available as one of three salts: clindamycin phosphate, clindamycin hydrochloride, or clindamycin nicotinamide.

Jul 26, 2023 · Clindamycin is an antibiotic that is usually reserved for treating anaerobic infections or other serious infections caused by gram-positive bacteria in penicillin-allergic people. The risk of C. difficile -associated diarrhea may be higher with …

Mar 15, 2024 · Because clindamycin therapy has been associated with severe colitis which may end fatally, it should be reserved for serious infections where less toxic antimicrobial agents are inappropriate. Diarrhea, colitis, and pseudomembranous colitis have been observed to begin up to several weeks following cessation of therapy with clindamycin.

Sep 17, 2024 · Clindamycin for intravenous use must be diluted prior to administration The concentration of clindamycin in diluent for IV infusion should not exceed 18 mg/mL. IV compatibility: The manufacturer's product information should be consulted; compatibility and duration of stability of drug mixtures varies according to concentration and other conditions.

Apr 10, 2024 · Clindamycin palmitate hydrochloride oral solution: Rapidly hydrolyzed in GI tract to active clindamycin. Clindamycin phosphate: Following IM or IV administration, rapidly hydrolyzed in plasma to active clindamycin. Following IM administration of clindamycin phosphate, peak serum concentrations occur within 3 hours in adults and 1 hour in children.

Jul 22, 2024 · Clindamycin can pass into breast milk and may cause side effects in the nursing baby. If you are breastfeeding while taking this medicine, call your doctor if your baby has diaper rash, redness or white patches in the mouth or throat, stomach discomfort, or diarrhea that is watery or bloody.

May 2, 2024 · Infection with Clostridium difficile (C. diff) is possible with clindamycin (and all antibiotics), which can cause severe diarrhea and an inflammation of the colon (colitis) and may occur more frequently with clindamycin compared to other antibiotics. This is a serious infection, but the risk is still low even with clindamycin use.

Oct 29, 2024 · Clindamycin Injection, USP, a clear colorless to pale yellow sterile solution, contains clindamycin phosphate, a water soluble ester of clindamycin and phosphoric acid. Each mL contains the equivalent of 150 mg clindamycin, 0.5 mg disodium edetate and 9.45 mg benzyl alcohol added as preservative in each mL.

Clindamycin Interactions There are 91 drugs known to interact with clindamycin , along with 4 disease interactions. Of the total drug interactions, 6 are major, 83 are moderate, and 2 are minor.

Concentrations in breast milk after oral administration of clindamycin 150 mg orally three times a day after at least 1 week of therapy have been reported at 1.2 mg/L (average, 6 hours after dosing) and at 0.3 to 1.2 mg/L between one and 6 hours after a single 150 mg dose.